KMID : 0363220160540050335
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Korean Journal of Dermatology 2016 Volume.54 No. 5 p.335 ~ p.340
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Clinicopathologic Features and Outcomes of Extramammary Paget¡¯s Disease
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Lee Seung-Woo
Kim Kea-Jeung Min Joon-Hong Heo Eun-Phil
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Abstract
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Background: Extramammary Paget¡¯s disease (EMPD) is a relatively rare cutaneous disorder. There are a few studies regarding the clinical features and prognostic factors of EMPD in Korean patients.
Objective: The aim of this study was to identify in detail the clinical findings and prognostic factors of EMPD in Korean patients.
Methods: A total of 19 patients with confirmed EMPD at our institution were included from January 2005 to December 2014. Clinical records and pathology slides of the patients were reviewed retrospectively.
Results: Patients¡¯ ages ranged from 50 to 87 years (median, 64.5 years), and incidence of EMPD was higher in men than in women (17£º2, male£ºfemale). The most common predilection site was the penoscrotal area in men and the vulva in women. All patients with EMPD had no underlying malignancy. Four of 19 patients treated with wide excision had local recurrence during the follow-up period. Two patients with deep dermal invasion died due to multiple metastases.
Conclusion: EMPD in Korea is characterized by its male predominance and penoscrotal location. Disease recurrence is common regardless of the surgical margin. Its prognosis could be associated with depth of invasion and lymph node metastasis.
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KEYWORD
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Extramammary Paget`s disease
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